About OS Fund


OS Fund was founded by Bryan Johnson in 2014 with a personal investment of $100 million. Johnson, Jeff Klunzinger and team worked to prove out the investment thesis that biology is programmable. We seek out platforms and enabling technologies, and have invested in many that have dramatically improved the world (i.e. Ginkgo Bioworks).

Our portfolio companies develop their own intellectual property to bring technologies to market that solve real-world challenges with significant impact. They also employ a business model that enables further discovery not just for themselves, but for the surrounding ecosystem as well. When these characteristics are present, we invest with high conviction early in the company’s life and remain closely involved thereafter.

We partner with entrepreneurs who are developing novel solutions that promise to rewrite operating systems (OS) and discover solutions to previously unsolvable problems.


We are actively investing in computationally driven companies utilizing artificial intelligence and machine learning to develop platform technologies in the following areas:


Synthetic Biology

Computationally Derived Therapeutics

Advanced Materials



We seek to partner with future literate entrepreneurs who understand our unique time and place in history, and who possess the ambition to author a better future for humanity. We develop relationships with our portfolio companies in their early stages and provide both strategic and financial support throughout their life cycle.



Our team’s founders have created, developed, and exited transformational companies, so we understand the process and the enormous difficulty of bringing something new into existence. We know that it takes an enormous leap of faith to raise outside capital and strive to be the kind of partner that we would choose to work with.

We aim to build long-term relationships with entrepreneurs that are based on honesty, transparency, and genuine support. We listen first, keep an open mind, and provide candid advice.


We are eager to support you in building your vision of the future, not to get in the way. As needed, we proudly help our entrepreneurs consider strategic and operational context, provide IP and commercialization support, and contemplate the financial and ethical consequences of major decisions. We find fulfillment in service, and meaning from team-based achievement.

We provide access to a cross-disciplinary network of entrepreneurs, innovators, and strategic partners who have similar or related goals, challenges, experiences, and interests.

We celebrate the fact that a meaningful number of our investments have been the result of an introduction from an existing portfolio company. We are honored to have earned the trust of our company founders, and look forward to continuing to serve as valued advisors and partners.

“Never in the history of mankind has the gap between imagination and creation been so narrow. With our new and powerful tools of creation including engineered biology, genomics, machine intelligence, robotics, software, and others, we can now create the kind of world we could previously only dream of. Where da Vinci could sketch, today we can build.”

- Bryan Johnson